d-Peptidase Activity in a Marine Mollusk Detoxifies a Nonribosomal Cyclic Lipopeptide: An Ecological Model to Study Antibiotic Resistance

In the marine environment, sessile cyanobacteria have developed chemical strategies for protection against grazers. turn, herbivores to circumvent these defenses and in certain cases even take advantage of them as shelter from their own predators. This is case Stylocheilus striatus, a sea hare that feeds on Anabaena torulosa, cyanobacterium produces toxic cyclic lipopeptides laxaphycin B family. S. striatus consumes without being affected by toxicity its compounds also uses it an invisibility cloak this article, using different substrates analogous B, we demonstrate presence enzyme digestive gland mollusk able biotransform derivatives. The belongs poorly known family d-peptidases are suspected be involved antibiotic resistance.